研究実績
英語論文
2024
Iida, S., Ide, S., Tamura, S., Sasai, M., Tani, T., Goto, T., Shribak, M.,Maeshima, K.(2024) Orientation-Independent-DIC imaging reveals that a transient rise
in depletion force contributes to mitotic chromosome condensation. Proceedings of the National Academy of Sciences 121, e2403153121.doi:10.1073/pnas.2403153121
Hibino, K., Sakai, Y., Tamura, S., Takagi, M., Minami, K., Shimazoe, M.A., Natsume, T., Kanemaki, M.T., Imamoto, N., Maeshima, K. (2024) Single-nucleosome imaging unveils that condensins and nucleosome-nucleosome
interactions differentially constrain chromatin to organize mitotic chromosomes.
Nature Communications 15, 7152.doi: 10.1038/s41467-024-51454-y
Semeigazin, A., Iida, S., Minami, K., Tamura, S., Ide, S., Higashi, K., Toyoda, A., Kurokawa, K., Maeshima, K. (2024) Behaviors of the nucleosomes with mutant histone H4s in euchromatic
domains of living human cells. Histochemistry and Cell Biology
https://link.springer.com/article/10.1007/s00418-024-02293-x
Otsuka, A., Minami, K., Higashi, K., Kawaguchi, A., Tamura, S., Ide, S., Hendzel, M.J., Kurokawa, K., Maeshima, K. (2024) Chromatin organization and behavior in RAS-transformed mouse fibroblasts.Chromosoma.https://doi.org/10.1007/s00412-024-00817-x
Iida, S., Ide, S., Tamura, S., Tani, T., Goto, T., Shribak, M., Maeshima, K. (2023) Orientation-Independent-DIC imaging reveals that a transient rise
in depletion force contributes to mitotic chromosome condensation.bioRxiv BIORXIV/2023/566679
https://doi.org/10.1101/2023.11.11.566679
2023
Maeshima, K., Iida, S., Shimazoe, M.A., Tamura, S., Ide, S. (2023) Is euchromatin really open in the cell? Trends in Cell Biology.
doi: 10.1016/j.tcb.2023.05.007
Smallwood, K., Watt, K. E.N.,Ide, S., Baltrunaite, K., Brunswick, C., Inskeep, K., Capannari, C., Adam, M.
P., Begtrup, A., Bertola, D. R., Cho, M., Demmer, L., Demo, E., Devinsky,
O., Gallagher, E. R., Sacoto, M. J. G., Jech, R., Keller-Ramey, J., Keren,
B., Kussmann, J., Ladda, R., Lansdon, L. A., Lunke, S., Mardy, A., McLaughlin,
H., McWalters, K., Person, R., Raiti, L., Saitoh, N., Saunders, C. J.,
Schnur, R., Skorvanek, M., Sell, S. L., Slavotinek, A., Sullivan, B. R.,
Stark, Z., Symonds, J.D., Wenger, T., Weber, S., Whalen, S., White, S.
M., Willaert, R., Winkelman, J., Zech, M., Zeidler, S., Maeshima, K., Stottmann,
R. W., Trainor, P. A, Weaver, K. N. (2023) Variant- and tissue-specific
effects underlie phenotypic heterogeneity in individuals with heterozygous
variants in POLR1A. The American Journal of Human Genetics110, 1–17.
https://doi.org/10.1016/j.ajhg.2023.03.014
Nozaki, T., Shinkai, S., Ide, S., Higashi, K., Tamura, S., Shimazoe, A. M., Nakagawa, M., Suzuki, Y., Okada, Y., Sasai, M., Onami, S., Kurokawa,
K., Iida, S., *Maeshima, K.(2022) Condensed but liquid-like domain organization of active chromatin
regions in living human cells. Science Advances. 9, eadf1488 Doi: 10.1126/sciadv.adf1488
https://www.science.org/doi/10.1126/sciadv.adf1488
2022
Minami, K., Iida, S., Maeshima, K. (2022) Chromatin organization and DNA damage. The Enzymes Volume LI: DNA damage and double strand breaks (Eds. K. Yoshikawa and
F. Tamanoi). Chapter 3. Academic Press/Elsevier.
https://doi.org/10.1016/bs.enz.2022.08.003
フリーリンク(11月16日まで)
Maeshima, K., Meshorer, E. (2022) Editorial Overview: Emerging concepts and tools
in genome organization and chromatin function in eukaryotes
Current Opinion in Cell Biology, 78, 102120
https://doi.org/10.1016/j.ceb.2022.102120
Maeshima, K.(2022) A phase transition for chromosome transmission when cells divide.
Nature.609, 35-36.
https://doi.org/10.1038/d41586-022-01925-3
Ide, S., Tamura, S., Maeshima, K. (2022) Chromatin behavior in living cells: lessons from single-nucleosome
imaging and tracking. BioEssays. 44, 2200043.
doi: 10.1002/bies.202200043
Iida, S., Shinkai, S.,Itoh, Y., Tamura, S., Kanemaki, M.T., Onami, S., Maeshima, K. (2022) Single-nucleosome imaging reveals steady-state motion of interphase
chromatin in living human cells. Science Advances. 8, eabn5626
doi: 10.1126/sciadv.abn5626
2021
Hansen, J.C., Maeshima, K., Hendzel, M.J. (2021) The solid and liquid states of chromatin. Epigenetics & Chromatin. 14, 50.
doi: 10.1186/s13072-021-00424-5
Ide, S., Sasaki, A., Kawamoto, Y., Bando, T., Sugiyama, H., Maeshima, K.(2021) Telomere-specific chromatin capture using a pyrrole–imidazole polyamide
probe for the identification of proteins and non-coding RNAs. Epigenetics & Chromatin. 14, 46.
doi: 10.1186/s13072-021-00421-8
Maeshima, K., Iida, S. (2021) Loopy world of cohesin eLife 10, e71585.
doi: 10.7554/eLife.71585
Itoh, Y., Woods, E.J.,Minami, K., *Maeshima, K., *Collepardo-Guevara, R.(2021) Liquid-like chromatin in the cell: What
can we learn from imaging and computational modeling? Current Opinion in Structural Biology.71, 123–135
doi: 10.1016/j.sbi.2021.06.004
Hoencamp, C., Dudchenko, O., Elbatsh, A. M.O., Brahmachari, S., Raaijmakers,
J. A., van Schaik, T., Cacciatore, Á. S., Contessoto, V., van Heesbeen,
R. G.H.P., van den Broek, B., Mhaskar, A. N., Teunissen, H., St Hilaire,
B. G., Weisz, D., Omer, A. D., Pham, M., Colaric, Z., Yang, Z., Rao, S.
S.P., Mitra, N., Lui, C., Yao, W., Khan, R., Moroz, L. L., Kohn, A., St.
Leger, J., Mena, A., Holcroft, K., Gambetta, M. C., Lim, F., Farley, E.,
Stein, N., Haddad, A., Chauss, D., Mutlu, A. S., Wang, M. C., Young, N.
D., Hildebrandt, E., Cheng, H. H., Knight, C. J., Burnham, T. L.U., Hovel,
K. A., Beel, A. J., Mattei, P.-J., Kornberg, R. D., Warren, W. C., Cary,
G., Gómez-Skarmeta, J. L., Hinman, V., Lindblad-Toh, K., di Palma, F.,
Maeshima, K., Multani, A. S., Pathak, S., Nel-Themaat, L., Behringer, R. R., Kaur,
P., Medema, R. H., van Steensel, B., de Wit, E., Onuchic, J. N., Di Pierro,
M., Lieberman-Aiden, E., Rowland, B. D. (2021) 3D genomics across the tree
of life reveals condensin II as a determinant of architecture type. Science 372, 984-989.
https://science.sciencemag.org/content/372/6545/984
doi:10.1126/science.abe2218
Maeshima, K.(2021) New door to understanding transcription, open with caution. In “Voices”,Molecular Cell, 81, 1581-1582
https://doi.org/ 10.1016/j.molcel.2021.03.046
Maeshima, K., Iida, S., Tamura, S. (2021) Physical nature of chromatin in the nucleus.
Cold Spring Harbor Perspectives in Biology. a040675.
doi:10.1101/cshperpsect.a040675
Cover Images
Itoh, Y., Iida, S., Tamura, S., Nagashima, R., Shiraki, K., Goto, T., Hibino, K., Ide, S., Maeshima, K. (2021) 1,6-hexanediol rapidly immobilizes and condenses chromatin in
living human cells. Life Science Alliance. 4, e20200100
https://www.life-science-alliance.org/content/4/4/e202001005
2020
Ide, T., Ochi, H., Imai, R., Maeshima, K. (2020) Transcriptional suppression of ribosomal DNA with phase separation. Science Advances. 6, eabb5953
Matsuyama, S., Maeshima, K., Shimura, M. (2020) Imaging intracellular elements and structure by synchrotron
X-ray with focusing system. Journal of Analytical Atomic Spectrometry. 35, 1279-1294.
https://doi.org/10.1039/D0JA00128G
Maeshima, K., Tamura, S., Hansen, J.C., Itoh, Y. (2020) Fluid-like chromatin: toward understanding the real chromatin
organization present in the cell.
Current Opinion in Cell Biology. 64, 77-89.
https://doi.org/10.1016/j.ceb.2020.02.016
Ashwin, S.S., Maeshima, K., Sasai, M. (2020) Heterogeneous fluid-like movements of chromatin and
their implications to transcription.Biophysical Reviews. 12, 461–468.
DOI: 10.1007/s12551-020-00675-8
Babokhov, M., Hibino, K., Ito, Y., Maeshima, K. (2020) Local chromatin motion and transcription. Journal of Molecular Biology. 432, 694-700.
https://doi.org/10.1016/j.jmb.2019.10.018
2019
Marie Anne O’Donnell (2019) Kazuhiro Maeshima : Excitement under the microscope (Interviewed by JCB as "People
& Ideas”)
Journal of Cell Biology 218, 3529–3530.
Doi: https://doi.org/10.1083/jcb.201910088
Ashwin, S.S., Nozaki, T., Maeshima, K., Sasai, M. (2019) Organization of fast and slow chromatin revealed by
single-nucleosome dynamics.
Proc Natl Acad Sci USA. 116, 19939-19944
https://doi.org/10.1073/pnas.1907342116
Prieto, E.I., Maeshima, K. (2019) Dynamic chromatin organization in the cell. Essays in Biochemistry. 63, 133-145.
doi: 10.1042/EBC20180054
Maeshima, K., Ide, S., Babokhov, M. (2019) Dynamic chromatin organization without the 30-nm fiber. Current Opinion in Cell Biology. 58, 95–104
doi: 10.1016/j.ceb.2019.02.003
Nagashima, R., Hibino, K., Ashwin, S.S., Babokhov, M., Fujishiro, S., Imai, R., Nozaki, T., Tamura, S., Tani, T., Kimura, H., Shribak, M., Kanemaki, M.T., Sasai, M., Maeshima, K. (2019) Single nucleosome imaging reveals loose genome chromatin networks
via active RNA polymerase II. Journal of Cell Biology. 218, 1511-1530.
doi: 10.1083/jcb.201811090
2018
Kazuhiro Maeshima(2018) How small numbers of long genomic DNA are stored in cells. Minorities
and Small Numbers from Molecules to Organisms in Biology (Editors Takeharu
Nagai and Yuichi Togashi), Springer Nature Singapore Pte Ltd.. Chapter 8, 53-58.
https://doi.org/10.1007/978-981-13-2083-5_8
Maeshima, K., Tamura, S., Shimamoto, Y. (2018) Chromatin as a nuclear spring.
Biophysics and Physicobiology. 15, 189-195.
doi: 10.2142/biophysico.15.0_189
https://www.jstage.jst.go.jp/article/biophysico/15/0/15_189/_article/-char/en
Maeshima, K., Hibino, K., Hudson, D.F. (2018) Condensins under the microscope. Journal of Cell Biology. 217, 2229–2231
doi: 10.1083/jcb.201804078
Maeshima, K., Matsuda, T., Shindo, Y., Imamura, H., Tamura, S., Imai, R., Kawakami, S., Nagashima, R., Soga, T., Noji, H., Oka, K., Nagai, T. (2018) A transient rise in free
Mg2+ ions coupled with ATP reduction promotes mitotic chromosome condensation.
Current Biology.28, 444–451
https://www.sciencedirect.com/science/article/pii/S0960982217316688
Hansen, J.C., Connolly, M., McDonald, C.J., Pan, A., Pryamkova, A., Ray,
K., Seidel, E., Tamura,S., Rogge, R., Maeshima, K. (2018) The 10-nm Chromatin Fiber and its Relationship to Interphase Chromosome
Organization.
Biochemical Society Transactions. 46, 67-76
DOI: 10.1042/BST20170101
2017
Nozaki, T., Hudson, F. D., Tamura, S., Maeshima, K. (2017) Dynamic chromatin folding in the cell. Nuclear Architecture and Dynamics(Editors Christophe Lavelle and Jean-Marc Victor). Chapter 4, 101-122
https://doi.org/10.1016/B978-0-12-803480-4.00004-1
Imai, R., Nozaki, T., Tani, T., Kaizu, K., Hibino, K., Ide, S., Tamura, S., Takahashi, K., Shribak, M., and Maeshima, K. (2017) Density imaging of heterochromatin in live cells using orientation-independent-DIC
microscopy.
Molecular Biology of the Cell. 28, 3349-3359
http://www.molbiolcell.org/content/28/23/3349.full
Nozaki, T., Imai, R., Tanbo, M., Nagashima, R., Tamura, S., Tani, T., Joti, Y., Tomita, M., Hibino, K., Wendt, K.S., Okada, Y., Nagai, T., Maeshima, K. (2017) Dynamic organization of chromatin domains revealed by super-resolution
live-cell imaging. Molecular Cell. 67, 282-293
http://dx.doi.org/10.1016/j.molcel.2017.06.018
Shimamoto, Y., Tamura, S., Masumoto, H., Maeshima, K. (2017) Nucleosome-nucleosome interactions via histone tails and linker
DNA regulate nuclear rigidity. Molecular Biology of the Cell28, 1580-1589
http://www.molbiolcell.org/content/28/11/1580.full
Shinkai, S., Nozaki, T., Maeshima, K., Togashi, Y. (2017) Bridging the dynamics and organization of chromatin
domains by mathematical modeling. Nucleus
http://dx.doi.org/10.1080/19491034.2017.1313937
Hibino, K., Kaizu, K., Takahashi, K., Maeshima, K. (2017) Combination approach of live-cell imaging and computational modeling
toward further comprehensive understanding genome, chromatin and epigenetics.
Epigenetics and Systems Biology (Editor Leonie Ringrose) Chapter 11, 225-238.
Doi.org/10.1016/B978-0-12-803075-2.00011-8
2016
Shinkai, S., Nozaki, T., Maeshima, K., Togashi, Y. (2016) Dynamic nucleosome movement tells Structural information
of topological chromatin domains in human cells. PLOS Computational Biology 12, e1005136.
Doi: 10.1371/ journal.pcbi.1005136
カバーイメージ
Kawamoto, Y., Sasaki, A., Chandrana, A., Hashiya, K., Ide, S., Bando, T., Maeshima, K., Sugiyama, H. (2016) Targeting 24 bp within Telomere Repeat Sequences
with Tandem Tetramer Pyrrole– Imidazole Polyamide Probes.
Journal of the American Chemical Society 138, 14100-14107.
Doi: 10.1021/jacs.6b09023
Chen, C., Hwa Lim, H., Shi, J., Tamura, S., Maeshima, K., Surana, U., and Gan, L. (2016) Budding yeast chromatin is dispersed
in a crowded nucleoplasm. Molecular Biology of the Cell 27, 3357-3368.
Doi: 10.1091/mbc.E16-07-0506
Sasaki, A., Ide, S., Kawamoto, Y., Bando, T., Murata, Y., Shimura, M., Yamada, K., Hirata,
A., Nokihara, K., Hirata, T., Sugiyama, H., Maeshima, K. (2016) Telomere Visualization in Tissue Sections Using Pyrrole-Imidazole
Polyamide Probes. Scientific Reports 6, 2926.
Doi: 10.1038/srep29261
Imai, R., Komeda, S., Shimura, M., Tamura, S., Matsuyama, S., Nishimura, K., Rogge, R., Matsunaga, A., Hiratani, I.,
Takata, H., Uemura, M., Iida, Y., Yoshikawa, Y., Hansen, JC., Yamauchi,
K., Kanemaki, MT, Maeshima, K. (2016) Chromatin folding and DNA replication inhibition mediated by a
highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex.
Scientific Reports 6, 24712.
Doi: 10.1038/srep24712
Maeshima, K., Rogge, R., Tamura, S., Joti, Y., Hikima, T., Szerlong, H., Krause, C., Herman, J., DeLuca,
J., Ishikawa, T., Hansen, J.C. (2016) Nucleosomal arrays self-assemble
into supramolecular globular structures lacking 30-nm fibers. EMBO J. 35, 1013-1149.
Doi: 10.15252/embj.201592660
Maeshima, K., Ide, S., Hibino, K., Sasai, M. (2016) Liquid-like behavior of chromatin.
Current Opinion in Genetics and Development 37, 36–45.
Doi: 10.1016/j.gde.2015.11.006
2015
Liang, Z., Zickler, D., Prentiss, M., Chang. F.S., Witz, G., Maeshima, K., Kleckner, N. (2015) Chromosomes progress to metaphase in multiple discrete
steps via global compaction/expansion (stress) cycles. Cell 161, 1124–1137.
http://dx.doi.org/10.1016/j.cell.2015.04.030
Kawamoto, Y., Sasaki, A., Hashiya, K., Ide, S., Bando, T., Maeshima, K., Sugiyama, H. (2015) Tandem trimer pyrrole-imidazole polyamide probes
targetting 18base pairs in human telomere sequences. Chemical Science 6, 2307-2312.
Doi: 10.1039/c4sc03755c
Maeshima, K. Kaizu, K., Tamura, S., Nozaki, T., Kokubo, T., Takahashi, K. (2015) The physical size of transcription
factors is key to transcriptional regulation in the chromatin domains.
Journal of Physics: condensed matter 27, 064116 (10pp).
Doi: 10.1088/0953-8984/27/6/064116
Lab Talk
2014
Maeshima, K., Nishino, Y., Joti, Y. (2014) Irregular organization in the human chromosomes
revealed by X-ray scattering. SPring-8 Research Frontiers 2013 32-33.
Pfd
Maeshima, K., Imai, R., Hikima, T., Joti, Y. (2014) Chromatin Structures Revealed by Small-angle
Xray Scattering Analysis and Computational Modeling. Methods 70, 154-161.
Doi:10.1016/j.ymeth.2014.08.008
Hirata, A., Nokihara, K., Kawamoto, Y., Bando, T., Sasaki, A., Ide ,S., Maeshima, K., Kasama, T., Sugiyama, H. (2014) Structual Evaluation of Tandem, Hairpin
Pyrrole-Imidazole Polyamides Recognizing Human Telomeres. Jouanal of American Chemical Society 136, 11546-11554.
Doi: 10.1021/ja506058e
Maeshima, K., Imai, R.,Tamura, S., Nozaki,T. (2014) Chromatin as dynamic 10-nm fibers. Chromosoma 123, 225-237.
Doi: 10.1007/s00412-014-0460-2
Nozaki, T., Imai, R., Tamura, S., Maeshima, K. (2014) Single nucleosome imaging in living human cells (Technical note,cover
image). Cytologia 79 (1) 1-2.
Doi: 10.1508/cytologia.79.1.1
Kuga, T., Nie, H., Kazami, T., Satoh, M., Matsushita, K., Nomura, F., Maeshima, K., Nakayama, Y., Tomonaga, T. (2014) Lamin B2 prevents chromosome instability
by ensuring proper mitotic chromosome segregation. Oncogenesis 3, e9.4
Doi: 10.1038/oncsis.2014.6
Maeshima, K., Funakoshi, T., Imamoto, N. (2014) Cell-fusion method to visualize interphase nuclear pore (NPC) formation.Methods in Cell Biology 122, 239-254.
2013
Kawamoto, Y., Bando, T., Kamada, F., Li, Y., Hashiya, K., Maeshima, K., Sugiyama, H. (2013) Development of a New Method for Synthesis of Tandem
Hairpin Pyrrole-Imidazole Polyamide Probes Targeting Human Telomeres. Journal of the American Chemical Society 135, 16468-16477.
Doi: 10.1021/ja406737n
Takata, H., Hanafusa, T., Mori, T., Shimura, M., Iida,Y., Ishikawa, K., Yoshikawa, K., Yoshikawa,
Y., Maeshima, K. (2013) Chromatin compaction protects genomic DNA from radiation damage.
PLOS ONE 8, e75622.
Doi: 10.1371/journal.pone.0075622
Nozaki, T., Kaizu, K., Pack, C.G., Tamura, S., Tani, T., Hihara, S., Nagai, T., Takahashi, K., Maeshima, K. (2013) Flexible and dynamic nucleosome fiber in living mammalian cells.
Nucleus 4, 349-356.
Doi: 10.4161/nucl.26053.
Shang, W. H., Hori, T., Martins, N. M., Toyoda, A., Misu, S., Monma, N., Hiratani, I., Maeshima, K., Ikeo, K., Fujiyama, A., Kimura, H., Earnshaw, W.C., Fukagawa, T., (2013) Chromosome Engineering Allows the Efficient Isolation of Vertebrate Neocentromeres. Dev Cell 24, 635-648.
Takata, H., Matsunaga, S., Maeshima, K. (2013) The organisation of genomic DNA in mitotic chromosomes: a novel view. In Greilhuber, J., Leitch, I., Wendel, J., Dolezel, J.(Eds.), Plant Genome Diversity 2, (pp: 33-34), Springer Verlag, Germany
2012
Hihara, S., Pack, C. G., Kaizu, K., Tani, T., Hanafusa, T., Nozaki, T., Takemoto, S., Yoshimi, T., Yokota, H., Imamoto, N., Sako, Y., Kinjo,
M., Takahashi, K., Nagai, T., Maeshima, K. (2012) Local Nucleosome Dynamics Facilitate Chromatin Accessibility in
Living Mammalian Cells.
Cell Reports 2, 1645-1656 .
Web
Joti, Y., Hikima, T., Nishino, Y., Kamada F., Hihara S., Takata H., Ishikawa, T., Maeshima, K. (2012) Chromosomes without a 30-nm chromatin fiber. Nucleus 3, 404-410.
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Takata, H., Nishijima, H., Maeshima, K., Shibahara, K. (2012) The integrator complex is required for integrity
of Cajal bodies. J Cell Sci. 125, 166-175.
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Nishino, Y., Eltsov, M., Joti, Y., Ito, K.,Takata, H., Takahashi, Y., Hihara, S., Frangakis, A.S., Imamoto, N., Ishikawa, T., Maeshima, K. (2012) Human mitotic chromosomes consist predominantly of irregularly
folded nucleosome fibres without a 30-nm chromatin structure. EMBO J. 31, 1644-53.
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2011
Takata, H., Maeshima, K. (2011) Irregular folding of nucleosomes in the cell: comment on "Cracking
the chromatin code: precise rule of nucleosome positioning" by Edward
N. Trifonov. Phys Life Rev 8, 51-52; discussion 69-72.
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Maeshima, K., Iino, H., Hihara, S., Imamoto, N. (2011) Nuclear size, nuclear pore number and cell cycle.
Nucleus 2, 113-118.
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2010
Maeshima, K., Hihara, S., Takata, H. (2010 (published in 2011) New insight into the mitotic chromosome
structure: irregular folding of nucleosome fibers without 30-nm chromatin
structure. Cold Spring Harb Symp Quant Biol 75, 439-444.
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Maeshima, K., Iino, H., Hihara, S., Funakoshi, T., Watanabe, A., Nishimura, M., Nakatomi, R., Yahata, K.,
Imamoto, F., Hashikawa, T., et al. (2010) Nuclear pore formation but not
nuclear growth is governed by cyclin-dependent kinases (Cdks) during interphase.
Nat Struct Mol Biol 17, 1065-1071
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Matsuyama, S., Shimura, M., Fujii, M., Maeshima, K., Yumoto, H., Mimura, H., Sano, Y., Yabashi, M., Nishino, Y., Tamasaku,
K., et al. (2010) Elemental mapping of frozen hydrated cells with cryo-scanning
X-ray fluorescence microscopy. X-Ray Spectrometry 39, 260-266.
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Iino, H., Maeshima, K., Nakatomi, R., Kose, S., Hashikawa, T., Tachibana, T., Imamoto, N. (2010)
Live imaging system for visualizing nuclear pore complex (NPC) formation
during interphase in mammalian cells. Genes Cells 15, 647-660.
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Maeshima, K., Hihara, S., Eltsov, M. (2010) Chromatin structure: does the 30-nm fibre exist in
vivo? Curr Opin Cell Biol. 22, 291-297.
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2009
Takemoto, A., Maeshima, K., Ikehara, T., Yamaguchi, K., Murayama, A., Imamura, S., Imamoto, N.,
Yokoyama, S., Hirano, T., Watanabe, Y., et al. (2009) The chromosomal association
of condensin II is regulated by a noncatalytic function of PP2A. Nat Struct Mol Biol. 16, 1302-1308.
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Nishino, Y., Takahashi, Y., Imamoto, N., Ishikawa, T., Maeshima, K. (2009) Three-dimensional visualization of a human chromosome using coherent
X-ray diffraction. Phys Rev Lett. 102, 018101.
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2008
Tahara, K., Takagi, M., Ohsugi, M., Sone, T., Nishiumi, F., Maeshima, K., Horiuchi, Y., Tokai-Nishizumi, N., Imamoto, F., Yamamoto, T., et al.
(2008) Importin-beta and the small guanosine triphosphatase Ran mediate
chromosome loading of the human chromokinesin Kid. J Cell Biol. 180, 493-506.
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Eltsov, M., Maclellan, K. M., Maeshima, K., Frangakis, A. S., and Dubochet, J. (2008) Analysis of cryo-electron
microscopy images does not support the existence of 30-nm chromatin fibers
in mitotic chromosomes in situ. Proc Natl Acad Sci USA 105, 19732-19737.
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Iwai, Y., Ikeda, T., Kojima, T. M., Yamazaki, Y., Maeshima, K., Imamoto, N., Kobayashi, T., Nebiki, T., Narusawa, T., and Pokhil, G.-P.
(2008) Ion irradiation in liquid of μm3 region for cell surgery. Applied
Physics Letters 92, 23509 (23503 pages).Iwai, Y., Ikeda, T., Kojima, T.
M., Yamazaki, Y., Maeshima, K., Imamoto, N., Kobayashi, T., Nebiki, T.,
Narusawa, T., and Pokhil, G.-P. (2008) Ion irradiation in liquid of μm3
region for cell surgery. Applied Physics Letters 92, 23509 (23503 pages).
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Maeshima, K., Eltsov, M. (2008) Packaging the genome : the structure of mitotic chromosomes.
J Biochem. 143, 145-53.Maeshima, K., Eltsov, M. (2008) Packaging the genome
: the structure of mitotic chromosomes. J Biochem. 143, 145-53.
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Wendt, K.S., Yoshida, K., Itoh, T., Bando, M., Koch, B., Schirghuber, E.,
Tsutsumi, S., Nagae, G., Ishihara, K., Mishiro, T., et al. (2008) Cohesin
mediates transcriptional insulation by CCCTC-binding factor. Nature 451, 796-801.
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2007
Funakoshi, T., Maeshima, K., Yahata, K., Sugano, S., Imamoto, F., Imamoto, N. (2007) Two distinct
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expression of tandemly associated transgenes. J Mol Biol. 374, 580-590.
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Maeshima, K., Yahata, K., Sasaki, Y., Nakatomi, R., Tachibana, T., Hashikawa, T.,
Imamoto, F., Imamoto, N. (2006) Cell-cycle-dependent dynamics of nuclear
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日本語総説
井手 聖、前島 一博「相分離モデルで理解する転写制御〜核小体と転写コンデンセート〜」「生体の科学」 74巻3号 2023 pp.234-239
DOI https://doi.org/10.11477/mf.2425201681
飯田史織、前島一博「生きた細胞のなかのヌクレオソームの動きをみる」
現代化学 東京化学同人 3月号 51-53, 2022.
飯田史織、前島一博「核内クロマチンの物理的な性質」月刊「細胞」2022年10月号特集「DNAの物性から理解するゲノムモダリティ」54, 12-15, 2022.
井手 聖、前島一博「核内構造体と液―液相分離 〜核小体と転写コンデンセートを中心に〜」生化学 94, 485-493, 2022.
doi:10.14952/SEIKAGAKU.2022.940485
島添將誠、井手聖、前島一博
「物性から迫るクロマチンの実像-相分離するクロマチンは液体か固体か?-」
実験医学 (増刊 セントラルドクマの新常識) 羊土社 40, 32-41, 2022
https://www.yodosha.co.jp/jikkenigaku/book/9784758104043/index.html
伊藤優志,井手聖, 前島一博「ヘキサンジオールは細胞内のクロマチンを凝縮させる」 生物物理 61, 385-388, 2021 doi: 10.2142/biophys.61.385
前島一博「生物物理学会とクロマチン」生物物理 2021年 61, 211ページ
doi: 10.2142/biophys.61.211
島本勇太、前島一博「ラミンとクロマチンの連携による核構造の維持メカニズム(Nuclear integrity maintenance by lamin and chromatin)」医学のあゆみ 2020年 272, 2, 157-161ページ
前島一博、松田知己、永井健治 「蛍光マグネシウムイオンプローブの開発とそれを利用した新たな染色体凝縮メカニズムの解明」マグネシウム(Journal of Japanese society for Magnesium Research)2019年 37, 13-18ページ
佐藤か奈、日比野佳代、前島一博「遺伝子が転写されるときのヌクレオソームの”動き”を捉えた!」academist Journal. 2019年5月
井手 聖、永島崚甫、前島一博「クロマチンダイナミクス〜クロマチンの物理的特性とその生物学的意味〜」実験医学増刊「染色体の新常識」36巻, 80-86ページ. 羊土社2018年11月
島本勇太、田村佐知子、前島一博「DNA は細胞のバネとしても働いている」生物物理、2018年 生物物理 58, 24-26ページ
日比野佳代・前島一博「少数支配を実現するゲノム―驚異のDNA収納術―」 実験医学、羊土社、2017年12月号 3211-3217ページ
野崎慎・前島一博「生細胞の超解像イメージングにより明らかにされたクロマチンドメインのダイナミックな構造」 ライフサイエンス新着論文レビュー 2017年8月
前島一博「1章 クロマチンの構造と染色体」 遺伝子発現制御機構(田村隆明・浦聖恵編集) 7-15 ページ、東京化学同人、2017 年 3 月
前島一博「少数のゲノムDNAが細胞の中に収納される仕組み」「少数性生物学の世界」第8章 61-68 ページ、 日本評論社、2017 年 3 月
前島一博「細胞内ゲノムDNAの折り畳み構造」科研費NEWS Vol. 3 14ページ「最近の研究成果トピックス」日本学術振興会、2016 年 12 月
日比野佳代、前島一博「一分子計測で探るクロマチンダイナミクス」うちのとくいわざ、日本免疫学会JSI Newsletter (2016) 24巻,
24ページ
前島 一博 「柔軟に収納されている生命の設計図」共済だよりレター、日本私立学校振興・共催事業団 発行 (2014) 11月号 14ページ
前島 一博 「教科書の染色体構造が変わる?!」 『はっきりわかる現代サイエンスの常識辞典』成美堂出版 2014年9月5日 80-81ページ
前島 一博 「DNAはなぜねじれているのですか?」子供の科学(2014) 8月号.46ページ。
前島 一博「DNA収納のなぞ:DNAは細胞内でどのように折りたたまれているのか?」「遺伝子が語る生命 38億年の謎ーなぜ、ゾウはネズミより長生きか?」悠書館2014年6月27日134-144ページ。
今井亮輔、海津一成、野崎 慎、前島一博、高橋恒一「定量的1分子蛍光イメージングと計算機シミュレーションを用いたゲノムダイナミクスの解析」、生化学(2014)86巻2号、192-200ページ
高田英昭、前島一博「ゲノムDNAの凝縮が放射線耐性をうみだす」日本アイソトープ協会広報誌「Isotope News」2014年 3月号 2-6ページ
前島一博「不規則な収納が生む自由-DNA収納の基本を問い直す-」「変わる」
生命誌年刊号 (2014) 111-117
前島一博「遺伝子を顕微鏡で見る」「遺伝子図鑑」(2013)226-227
前島一博「放射光によるヒト染色体の構造解析」放射光(2013)26巻4号(7月号) 206-213
野崎慎、前島一博「30nmクロマチン線維は存在しない!」化学と生物 (2013) 51, 177-182
前島一博、城地保昌、西野吉則、,高田英昭、鎌田福美、日原さえら「ヒトゲノムDNAの不規則で柔軟な収納原理」生物物理(2013) 53, 4-10
日原さえら , 前島一博「分裂期染色体の構築原理」実験医学(2009) 27 2723-2731
前島一博 , 西野吉則「コヒーレントX線回折によるヒト染色体構造の3次元観察」生物物理(2009) 49 298-300
前島一博 「染色体の内部構造を見る」細胞工学別冊「電子顕微鏡で読み解く生命のなぞ(ナノワールドに迫るパワフル技術入門)(2008) 121-129
前島一博、吉田圭介、白髭克彦「姉妹染色体間の接着因子、コヒーシンの新たな機能」蛋白質核酸酵素 (2008) 53, 1337-1344
前島一博、今本尚子「細胞周期における核膜孔のダイナミクス」生化学 (2008) 2月号, 118-124
前島一博,矢幡一英,今本文男,今本尚子「インスレーター/バウンダリー配列を用いた複数の導入遺伝子を安定的に発現させるシステム 」羊土社バイオテクノロジージャーナル(2007)9-10月号,557-563
前島一博 「染色体の凝縮メカニズム」細胞工学 (2006) 25, 486?491.
前島一博 「染色体:生命を担う驚異の構造」蛋白質核酸酵素 (2005) 50, 1620-1629.
今本文男、曽根岳史、矢幡一英、佐々木ゆかり、高木昌俊、前島一博、今本尚子、「生細胞への複数種cDNAの共導入と発現量の制御」蛋白質核酸酵素(2005)
50, 1637-1648